Critical Limb Ischemia CLI Key Facts

Critical Limb Ischemia (CLI) is among the most severe forms of peripheral artery disease. It is characterised by chronically reduced blood flow to the limbs. CLI is presented by ischemic rest pain, non-healing ulcer, or gangrene development in the lower extremities. Critical Limb Ischemia (CLI) results from progressive arterial occlusion due to atherosclerosis and is associated with a high risk of limb loss and cardiovascular mortality if left untreated. Early diagnosis and timely revascularisation are essential to prevent limb from complete loss and reduce other complications to enhance patient outcomes.
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